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Rare Mutant Cells Glimpsed: Imaging System May Help Understand Origins Of Cancer |
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Wednesday, 23 July 2008 |
MIT biological engineers have developed a new imaging
system that allows them to see cells that have undergone a specific
mutation. The work, which could help scientists understand how precancerous
mutations arise, marks the first time researchers have been able to
pinpoint the number and location of mutant cells--cells with a
particular mutation--in intact tissue. In this case, the researchers
worked with mouse pancreatic cells.
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NIST trumps the clumps: Making biologic drugs safer |
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Wednesday, 23 July 2008 |
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Scientists at the National Institute of Standards and Technology
(NIST) have developed a technique to measure the formation of clumps of
proteins in protein-based pharmaceuticals. This first systematic study*
clarifies the conditions under which scientists can be assured that
their instruments are faithfully measuring the formation of protein
aggregates, a major concern because of its impact on quality control
and safety in biologic drug manufacturing.
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FloCyte Regionals: A Gateway to the World of Flow |
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Monday, 21 July 2008 |
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Sunny Davis, California was the site of the latest FloCyte Regional Intensive Short Course in Flow Cytometry. This course is designed to provide the background, theory and hands-on training necessary to put scientists from all walks in the driver's seat of their own flow experiements. These courses are ongoing and may be in your area soon. If you are thinking about signing up, and want a user's perspective of a week in the life of a FloCyte attendee, then read more...
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Calcium May be the Key to Understanding Alzheimer's Disease |
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Monday, 21 July 2008 |
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Researchers at the University of Pennsylvania School
of Medicine have shown that mutations in two proteins associated with
familial Alzheimer's disease disrupt the flow of calcium ions within
neurons. The two proteins, called PS1 and PS2 (presenilin 1 and 2),
interact with a calcium release channel in an intracellular cell
compartment.
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